Clinical Research Centre Hospital Queen Elizabeth I (CRC QEHI) also previously known as CRC Sabah, was first established as part of the Network of Clinical Research Centres of the Ministry of Health (MOH) in 2008. It has been operational since 2008 with the aim to promote, support and conduct quality and ethical clinical research to improve patients’ outcome in HQEI. CRC QEHI undertakes clinical research, and provides research-related administrative services and training courses including research methodology, medical biostatistics and Good Clinical Practice (GCP) workshops.

Previously since 2008, CRC Sabah was temporarily located in the Continuous Ambulatory Peritoneal Dialysis Unit (CAPD Unit) in Queen Elizabeth Hospital. In March 2010, it officially moved to its own premise, a modest colonial bungalow converted into office, within the Queen Elizabeth Hospital I compound. Since the move, vast expansion of research facilities within the hospital has been done to support the increasing activities of research trainings, Investigator Initiated Research (IIR) and Industry Sponsored Research (ISR) in the hospital.