The Clinical Research Centre at Sarawak General Hospital (CRC SGH) was the third CRC established by the Ministry of Health (MOH) as part of the CRC network after the ones in Kuala Lumpur Hospital and Penang General Hospital. It was established with the aim to foster closer clinical research and cooperation at MOH hospitals in Malaysia by providing assistance in research proposals and writing, research funding and grant applications. The CRC-SGH also organises training workshops in biostatistics and research methodology and good clinical practice and assists in presentations at local and international scientific meetings. Following the increase in international multicentre clinical trials, especially in the fields of cardiovascular disease and oncology over the last five years, CRC-SGH improved its facilities and support services to strengthen the tradition of medical and epidemiological research in Sarawak.