Clinical Research Centre
Hospital Queen Elizabeth II
Sabah
WhoWe Are
Established in December 2011 as part of the Ministry of Health's Clinical Research Centre Network, the Clinical Research Centre Hospital Queen Elizabeth II (CRC HQEII) is led by Dr. Liew Houng Bang. Its mission is to promote, support, and conduct high-quality and ethical clinical research to enhance patient outcomes at HQEII.
Research Interest:
- Clinical Trials
- Digital Health & Telemedicine Research
- Health Economics Research
Disease Area:
- Cardiovascular
- Endocrinology
OurTeam
InvestigatorsHighlight
Head of CRC, Head of Cardiology Department Hospital Queen Elizabeth II, Sabah
Email: hbliew@moh.gov.my
MBBChBAO, FRCP (Edin), AM (Mal), FNHAM, FAPSIC
Areas of interest: Cardiology, clinical research, and specialized techniques and technologies
Dr. Liew Houng Bang is a leading cardiologist and interventional specialist at Queen Elizabeth II Hospital. With a medical degree from The Queen’s University of Belfast and advanced cardiology training in Malaysia and Australia, he has performed over 6000 PCI procedures. As Head of the Cardiology Department, Dr. Liew is actively involved in clinical research, including phase II drug trials such as AEGIS2, VICTOR, ZEUS, SELECT, LIBREXIA-AF, LIBREXIA-ACS, ARTEMIS, and BALANCE-D HF. His expertise extends to drug-coated balloons, digitalization, and AI in cardiology. Dr. Liew has been a principal investigator in significant trials like REDUCE, LEADERS IV, Onyx One, REVERSE, and TRANSFORM II. He continues to contribute to advancements in heart failure management and interventional cardiology. He also plays a key role in national and international cardiology conferences.
Research Highlights
Phase II Drug Trials:
AEGIS2, VICTOR, ZEUS, SELECT, LIBREXIA-AF, LIBREXIA-ACS, ARTEMIS, and BALANCE-D HF
Recent Publications
Project Highlights
Discover the nutritional benefits and anti-diabetic potential of Sabah's traditional rice. Our research identifies key components, evaluates their effects on diabetes, and ensures safety through toxicology analysis. This study aims to offer natural dietary solutions for diabetes management, benefiting patients worldwide.
This study explores an innovative approach at our clinical research center to enhance heart failure (HF) patient care through digital health. Utilizing the Wizard of Oz methodology, we observe and model interactions between patients and a conversational agent designed to assist with HF self-management and medication adherence via a mobile application. By simulating a human-like agent, we aim to gather critical insights into user needs and behaviors, paving the way for more effective and empathetic digital health interventions
This project evaluates the financial implications of adopting empagliflozin within the healthcare system, considering treatment costs and healthcare resource utilization. It aims to provide insights into the potential economic impact and inform healthcare decision-making.
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NMRR-21-1388-60672 |
Wizard of Oz Observational Study: For the Development of Conversational Template for MARIA (Medical Assistance Response Intelligent Agent) in Assisting Patients in HF Self-Management and Medication Adherence via ReportCare Mobile App (MARIA) |
| NMRR-22-00340-BY2 | Budget Impact Analysis of Empagliflozin in the Treatment of Heart Failure with Reduced Ejection Fraction - (BIAEmHeart) |
| NMRR-22-01179-JOW | Green Heart Project (Phase II) - An Observational, Prospective Study using ReportCare – an AI-Powered Mobile App for Chronic Heart Failure Patient Remote Monitoring |
| NMRR-21-1480-60316 | A Therapeutic Intervention via Diet Modification using Sabah Traditional Rice for type 2 Diabetes Mellitus patients. |
| NMRR-21-1105-59953 | Brugada Syndrome associated Genetic variants in the Malaysian Adult Population: A Case Control study |
| NMRR-24-01483-0GV | A Decade Experience of Treating Denovo Chronic Total Occusion with Drug Coated Balloon and Drug Eluting Stents (SHC CTO PCI) |
| NMRR-21-760-59664 | ZEUS - Effects of ziltivekimab versus placebo on cardiovascular outcomes in participants with established atherosclerotic cardiovascular disease, chronic kidney disease and systemic inflammation |
| NMRR-21-01966-OTR | A Pivotal Phase 3 Randomized, Placebo-controlled Clinical Study to Evaluate the Efficacy and Safety of the sGC Stimulator Vericiguat/MK-1242 in Adults With Chronic Heart Failure With Reduced Ejection Fraction |
| NMRR-12-928-13680 | Global SYMPLICITY Registry (GSR) Denervation Findings in Real World (DEFINE) is referred to as the GSR DEFINE study |
List of Publications associated with CRC HQEII
- Risk Factors for Mortality in Post-Myocardial Infarction Patients: Insights from the Improve SCA Bridge Study
- Kumar, D., Bardooli, F., Chen, W. J., Huang, D., Sankardas, M. A., Ahmed, W. H., Liew, H. B., Gwon, H. C., Van Dorn, B., Holmes, T., Thompson, A., & Zhang, S.
- A Real-World Experience of a Prescribing Policy for SGLT2-Inhibitors in HFrEF in a Malaysian Public Tertiary Cardiac Centre
- Sim Yong, V., How Yen, C., Saharudin, S., Ling Tan, S., Fadhilah Kaukiah, N., & Bang Liew, H.
- Examining Health-Related Quality of Life in Ambulatory Adult Patients with Chronic Heart Failure: Insights from Malaysia using EQ-5D-5L
- Tan, Y. J., Ong, S. C., Yong, V. S., Khor, W. W., Pang, L. J., Choong, Y. Y., Zameram, A. M., Tan, L. Y., Voo, J. Y. H., Lam, K. K., Yen, C. H., Wahab, M. J. A., & Abdulla, Z. B.
- Translation, cross-cultural adaptation, and psychometric validation of the Malay version of the Assessment of Quality of Life—6 Dimensions (Malay-AQoL-6D) instrument among Malaysians living with chronic heart failure
- Yi Jing Tan, Siew Chin Ong, Sook Pin Goh, Gang Chen, Vee Sim Yong, Wei Wern Khor, Ying Min Kan, Yong Ying Choong, Ainul Mardhiyyah Zameram, Lin Yuing Tan, James Yau Hon Voo, Kar Kei Lam, Chia How Yen, Mohamed Jahangir Abdul Wahab, and Zarina Banu Abdulla
Services at CRC Hospital Queen Elizabeth II
CRC HQEII conducts Clinical Research
- Industrial Sponsored Research (ISR)
- Investigator Initiated Research (IIR)
Meet Our Collaborators
CRC Hospital Queen Elizabeth II, Sabah
Main Phone: +6088-324600 ext. 2019
Email: crcenquiry@gmail.com
