Clinical Research Centre
Hospital Seri Manjung
Perak
WhoWe Are
Clinical Research Centre Hospital Seri Manjung (CRC HSM) was established since 2011, with the collaboration of Clinical Research Malaysia. We aim to improve patients’ health through ethical and quality clinical research. We manage Investigator Initiated Research (IIR) as well as Industry-Sponsored Research (ISR). The availability of medical facilities and investigators at the site contribute to the increasing number of clinical research in Hospital Seri Manjung. In addition, there are ongoing research consultations throughout the year to assist our colleagues in conducting research, such as National Medical Research Register (NMRR) registration, protocol development, literature search, statistical analysis, manuscript write-up and assistance in submission for publication of research papers. We also provide research-related trainings such as Good Clinical Practice (GCP) Workshop, Introduction to Clinical Research (ICR) Workshop, Basic Biostatistics Workshop, Proposal Writing Workshop, Literature Search and Referencing Workshop, Scientific Writing Workshop, NMRR Registration Workshop, etc.
OurTeam
InvestigatorsHighlight
Head of CRC, Consultant Paediatrician, Hospital Seri Manjung (HSM
Email: ngashihhang@gmail.com
MBBS, MRCPCH
Areas of interest: Paediatric Asthma, Diabetes, Neonatology
Awards and achievements:
- Excellent Service Award, Ministry of Health Malaysia - 2006, 2011
Dr. Nga, who holds an MBBS and MRCPCH in Paediatrics, earned his GCP certification in 2006 and soon began his first Industry Sponsored Research (ISR). His subsequent ISRs have focused on paediatric asthma, Type 2 diabetes, and RSV infections. He is currently the head of the Clinical Research Centre at Hospital Seri Manjung, a 305-bed minor specialist hospital offering services in various fields including Internal Medicine, Obstetrics, Surgery, Paediatrics, and more. Dr. Nga has conducted local audits on topics such as neonatal intravenous cannulation, patient falls in paediatric wards, sexual abuse in suburban areas, and iron overload in thalassemia. He also published a case report on Refractory Kawasaki Disease in the Medical Journal of Malaysia.
Recent Publications
Research Work Involvement
- Oral Diosmectite reduces stool output and diarrhoea duration in children with acute watery diarrhoea
- Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma (as Country Coordinating PI)
- T2NOW: A 26-Week, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Phase 3 Trial with a 26-Week Safety Extension Period Evaluating the Safety and Efficacy of Dapagliflozin 5 and 10 mg, and Saxagliptin 2.5 and 5 mg in Pediatric Patients with Type 2 Diabetes Mellitus Who Are Between 10 and Below 18 Years of Age
- ReViral: A Phase 2 Open-Label Study in Infants with REspiratory Syncytial VIRus Lower RespirAtory Tract Infection, Followed by a DoubLe-blind, Placebo controlled Part, to Evaluate the Safety, Tolerability, Pharmacokinetics and Antiviral Effect of RV521 (REVIRAL 1)
- MK 1654: A Phase 2b/3 Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-1654 in Healthy Pre-Term and Full-Term Infants
- A randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, and tolerability of dexpramipexole administered orally for 52 weeks in participants with severe eosinophilic asthma (EXHALE-2)
- An Interventional, Phase 1b, Randomized, Double-Blind, Placebo-controlled , Multi-center, Dose-finding Study To Evaluate Safety, Tolerability and Pharmacokinetics Of SISUNATOVIR In Pediatric Participants up to age 60 months with Respiratory SyncitialVirus (RSV) Lower Respiratory Tract Infection (LRTI)
Project Highlights
- This is a quasi-experimental study which will be conducted among students at the selected high schools under Manjung District Education Office, Perak.
- This study aims to determine the impact of brief e-cigarettes (e-cig) educational intervention on the knowledge and perception of e-cig harmfulness as well as intention to try among adolescents in Manjung District, Perak, Malaysia.
- This is a cross-sectional study conducted among caretakers of paediatric patients who present at the pharmacy counter of health clinics under Kampar District Health Office.
- This study aims to determine the extent of knowledge and practice of caretakers of paediatric patients on the storage of oral liquid medications.
- This is a retrospective cohort study conducted at Hospital Tengku Ampuan Rahimah, Klang involving retrospective review of hospitalized maternal cases with suspected pulmonary embolism (PE) who had undergone Computed Tomography Pulmonary Angiogram (CTPA) examination.
- This study aims to study the prevalence and clinical features of PE during pregnancy and puerperium.
- This project involves two audits on the case notes of Transfusion Dependent Thalassemia (TDT) patients requiring regular blood transfusion in paediatric ward of Hospital Seri Manjung (HSM).
- It aims to increase the usage of Algorithm of Management of Iron Chelation Therapy (ICT) in TDT patients in paediatric ward, HSM.
- This project involves three audits on the admission notes of patients hospitalized in medical wards of Hospital Seri Manjung (HSM).
- It aims to increase the use of risk assessment model for Venous Thromboembolism (VTE) and bleeding as well as to improve the appropriateness of VTE prophylaxis initiation.
List of Publications associated with CRC HSM
- Lost years, mortality burden: the impact of COVID-19 pandemic on premature death due to road traffic accidents in a northern state in Malaysia
- Premaa Supramaniam, Suria Junus, Lina Hashim, Shoen Chuen Chiew, Philip Rajan Devesahayam
- Development of a novel questionnaire to assess knowledge, attitude and practice towards medical disorders in pregnancy among clinicians
- Thai Lun Tan, Shoen Chuen Chiew, Qinglin Lau, Thanusha, Mahmoud Danaee, Manisha
Services at CRC Hospital Seri Manjung
CRC HSM provides training through workshops and consultations:
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Research consultations:
- Proposal/Protocol development
- Research question/objective hypothesis
- Study design
- Sample size planning
- Sampling technique
- Instrument/questionnaire
- Statistical planning
- Protocol review
Assist with statistical software:
- Data entry/management
- Data analysis
- Statistical writing
- Abstract/report writing
- NMRR assistance
- DG approval for presentation/publication
- Institution approval
Training:
- Good Clinical Practice (GCP) Workshop
- Introduction to Clinical Research (ICR) Workshop
- Basic Biostatistics Workshop
- Proposal Writing Workshop
- Literature Search and Referencing Workshop
Further info on upcoming activities
CRC Hospital Seri Manjung, Perak
Main Phone: +605-689 6600 ext. 6639
