Clinical Research Centre
Institut Kanser Negara
Putrajaya
WhoWe Are
Clinical Research Centre Institut Kanser Negara (CRC IKN) was formally established on 30th October 2014 with the function to coordinate and monitor research activities conducted within IKN premises. Various research-related activities, trainings and consultations have been held every year continuously to promote research activities and to create a good and ethical research foundation among IKN researchers.
OurTeam
InvestigatorsHighlight

Head of CRC, Clinical Oncologist and Deputy Head of Department of Radiotherapy and Oncology, IKN
Email: florencefui@yahoo.com
MCO (UM), MBBS (UM)
Areas of interest: Lung cancer, Hepatobiliary cancer, Genitourinary cancer, Head and neck cancer, Neuroendocrine cancer
Awards and achievements:
- Top Recruiter for RAINBOW and PARACHUTE Trials, 2018
- Clinical Trial Site of the Year, 2018
- Lead Trainer for Master of Clinical Oncology Program in IKN
- Member of Specialty Subcommittee for Education (SSC-Edu) for Clinical Oncology, Medical Education Committee (MEC), Majlis Perubatan Malaysia (MPM)
- External Reviewer for Traditional and Complementary Medicine Practice Guideline on Herbal Therapy as Adjunct Treatment for Cancer Edition 2, 2018
- Member of Clinical Practice Guideline for Nasopharyngeal Carcinoma (Malaysia) Development Group, 2017
- Expert Committee for the Effect of Chinese Herbal Medicine as an Adjunct Management of Fatigue and Muscle Weakness in Cancer Patients Receiving Chemotherapy under Health Technology Assessment, 2017
Dr. Wong Yoke Fui is a distinguished clinical oncologist with over a decade of experience in the field. She currently serves as the Deputy Head of the Radiotherapy and Oncology Department at Institut Kanser Negara (IKN) and has led the Clinical Research Centre (CRC) IKN since 2016. Dr. Wong earned her MBBS degree from Universiti Malaya in 2005 and completed her Master of Clinical Oncology at the same institution in 2014. She is also the Lead Trainer for the Master in Clinical Oncology program at IKN. Since joining IKN in 2014, Dr. Wong has been actively engaged in both Industry Sponsored Research (ISR) and Investigator Initiated Research (IIR), alongside her clinical duties. Her research primarily focuses on solid tumours, with a special interest in head and neck cancers and neuroendocrine tumours. Over the past eight years, Dr. Wong has significantly contributed to oncology trials, serving as Principal Investigator in 22 clinical trials and as Sub-Investigator in an additional 10 trials across various cancer types. Her exceptional dedication to advancing cancer research and improving patient outcomes has earned her the respect and admiration of both colleagues and patients
Research Highlights
Multicentre Clinical Epidemiological Study of Female Breast Cancer in a Multi-ethnic Malaysian Setting (Epi-Can)
Epi-Can is a multicentre retrospective cohort study that involves seven of the Ministry of Health (MOH) hospitals in Malaysia. This study aimed to determine the nature of breast cancer patients’ presentation, diagnosis, management of treatment, treatment-induced cardiovascular complications and survival while describing the variation across age, socioeconomic, geographic regions, ethnic differences and its trend over time in Malaysia. The results of this study will aid in observing secular changes as well as long-term outcomes for breast cancer patients in real-world clinical practice.
Recent Publications
Project Highlights
Multicentre Clinical Epidemiological Study of Female Breast Cancer in a Multi-ethnic Malaysian Setting (Epi-Can)
NMRR ID-22-01338-NBF
Epi-Can is a multicentre retrospective cohort study that involves seven of the Ministry of Health (MOH) hospitals in Malaysia. This study aimed to determine the nature of breast cancer patients’ presentation, diagnosis, management of treatment, treatment-induced cardiovascular complications and survival while describing the variation across age, socioeconomic, geographic regions, ethnic differences and its trend over time in Malaysia. The results of this study will aid in observing secular changes as well as long-term outcomes for breast cancer patients in real-world clinical practice.
Contact: Shridevi Subramaniam
shridevi@crc.gov.my

List of Publications associated with CRC IKN
- Survival Analysis of Endometrium Cancer Patients From Three Main Cancer Referral Centres in Malaysia
- Mohd Anuar Siti Fatimah Zahra, Subramaniam Shridevi, Wong Yoke Fui, Abdul Malik Rozita, Yehgambaram Prathepamalar
Services at CRC Institut Kanser Negara
CRC IKN conducts Clinical Research & Trials
- Conduct research according to the MOH priority areas.
- Conduct and provide technical support for clinical trials conducted in IKN.
- Ensure ethical clearance for all research to be carried out in IKN.
Meet Our Collaborators

CRC Institut Kanser Negara
Main Phone: +603-8892 5555 ext 4168
Email: crc.ikn@gmail.com